Precise detection of cell-type-specific domains in spatial transcriptomics

2024.10.28

Recently, the research collaboration among the Bioinformatics & Intelligent Medicine team, Southern Medical University Zhujiang Hospital, Tianjin Medical University Cancer Hospital, etc....

Pairpot: a database with real-time lasso-based analysis tailored for paired single-cell and spatial transcriptomics

2024.11.06

ecently, the Bioinformatics & Intelligent Medicine team has published “Pairpot: a database with real-time lasso-based analysis tailored for paired single-cell and spatial transcriptomics” in the journal Nucleic Acids Research....

Predicting and visualizing vertebrate genome duplication database

2022.08.01

we constructed the DupScan database (https://dupscan.sysumeg.com/) by integrating 106 chromosomal-level genomes, which can analyze and visualize synteny at both the gene and genome scales, visualize the Ka, Ks, and 4DTV values, and...

Weakly supervised model for HER2 status prediction in breast cancer

2024.07.02

Recently, the research collaboration between the Bioinformatics & Intelligent Medicine team and Tianjin Medical University Cancer Hospital has resulted in the publication titled "PhiHER2: Phenotype-informed weakly supervised model for HER2 status prediction from...

NeoTCR: an immunoinformatic database of experimentally-supported functional neoantigen-specific TCR sequences.

2024.05.08

The lab team published “NeoTCR: an immunoinformatic database of experimentally-supported functional neoantigen-specific TCR sequences.” in Genomics, Proteomics & Bioinformatics...

SCDD: a novel single-cell RNA-seq imputation method with diffusion and denoising

2022.09.07

We propose a method called SCDD to impute dropout events and verify its advantages over traditional methods...

LPAD: using network construction and label propagation to detect topologically associating domains from Hi-C data

2023.05.03

LPAD is a novel algorithm designed to identify topologically associated domain (TAD) structures from the Hi-C contact matrix...

HiBrowser: Hi-C Multiomics Data Synchronization Visualization Browser

2023.07.30

We desigen a 3D Genome visualization Browser named HiBrowser. It is an out-of-the-box, interactive and dynamic browser that allows for flexible and dynamic reconstruction of custom annotation ...

A new method of DTI prediction to maintain the consistency of Medicinal chemistry properties and functions

2022.11.02

The lab team published “Drug–Protein interaction prediction by correcting the effect of Incomplete information in heterogeneous information” in Bioinformatics...

A New DPI Prediction Method for Correcting the Impact of Incomplete Information in Multisource Heterogeneous Networks

2021.10.15

The lab team published "Autoencoder-based drug–target interaction prediction by preserving the consistency of chemical properties and functions of drugs" in Bioinformatics……

The Center for Bioinformatics and Intelligent Medicine Participates in BRICS COVID-19 Theme Workshop

2021.05.01

As a representative of young Chinese scientists, the Director of the Center for Bioinformatics and Intelligent Medicine was invited to...